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更新时间:2021.12.20
总访问量:10

周俊平

| 博士 副研究员 请选择

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办公地址: 生物楼A327

办公电话:

电子邮箱: zhoujp@zjut.edu.cn

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  • 个人简介

    周俊平,男,博士、特聘副研究员、硕士生导师,江西抚州人。20191月获得江南大学发酵工程专业博士学位,20192月到20208月期间在美国奥本大学从事生物燃料制备的博士后研究。主要从事酶的理性设计及定向改造、生物级联反应及代谢工程等方面课题,以第一或共一作者在ACS catalysis Advanced Materials, Current Opinion in Chemical Biology, Biotechnology JournalSCI期刊发表论文,影响因子总和大于50,并获多项专利授权。参与国家863项目等国家级与省部级项目,担任Frontier in Bioengineering and Biotechnology3 BiotechReview editor,获第三届互联网+”大学生创新创业大赛全国铜奖及江苏省一等奖。

  • 科研项目

    大肠杆菌合成苏氨酸衍生的非天然氨基酸底盘细胞设计与构建,国家自然科学基金青年基金项目,2022.01-2024.12,主持

  • 科研成果

    代表性论文论著

    1.       J.P. Zhou, R.Z. Zhang,* T.W. Yang, Q.L. Liu, J.X. Zheng, F. Wang, F. Liu, M.J. Xu, X. Zhang, Z.M. Rao.* 2018. Relieving allosteric inhibition by designing active inclusion bodies and coating of the inclusion bodies with Fe3O4 nanomaterials for sustainable 2-oxobutyric acid production. ACS catalysis, 8(9), 8889-8901.

    2.       J.P. Zhou, Z. Chen, Y. Wang. * 2020. Bioaldehydes and beyond: expanding the realm of bioderived chemicals using biogenic aldehydes as platforms. Current Opinion in Chemical Biology, 59, 37-46.

    3.       J.P. Zhou, Y.L. Wang, J.J. Chen, M.J Xu,* T.W. Yang, J.X. Zheng, X. Zhang, Z.M. Rao.* 2019. Rational engineering of Bacillus cereus leucine dehydrogenase towards α-keto acid reduction for improving unnatural amino acid production. Biotechnology Journal, 14(3), e1800253.

    4.       R.Z. Zhang,* J.W. Jiang, J.P. Zhou, Y. Xu,* R. Xiao, X.H. Xia, Z.M. Rao.* 2018. Biofunctionalized kiwifruit-assembly of oxidoreductases in mesoporous ZnO/carbon nanoparticles for efficient asymmetric catalysis. Advanced Materials, 1705443.

    5.       L.Z. Tian†, J.P. Zhou†, Q.L. Lv, F. Liu, T.W. Yang, X. Zhang, M.J. Xu*, Z.M. Rao*. 2021. Rational engineering of the Plasmodium falciparum L-lactate dehydrogenase loop involved in catalytic proton transfer to improve chiral 2-hydroxybutyric acid production. International Journal of Biological Macromolecules, https://doi.org/10.1016/j.ijbiomac.2021.02.144.

    6.       F. Liu†, J.P. Zhou†, M.J. Xu, T.W. Yang, M.L. Shao, X. Zhang*, Z.M. Rao*. 2020. One-pot biocatalytic preparation of enantiopure unusual α-amino acids from α-hydroxy acids via a hydrogen-borrowing dual-enzyme cascade.Catalysts, 10, 1470.

    7.       J. Feng†, J. Zhang†, Y.C. Ma†, Y.M. Feng, S.J. Wang, N. Guo, H.J. Wang, P.X. Wang, P. Jiménez-Bonilla, Y.Y. Gu, J.P. Zhou, Z.T. Zhang, M.F. Cao, D. Jiang, S.N. Wang, X.W. Liu, Z.Y. Shao, I. Borovok, H.B. Huang* & Y. Wang*. 2021. Renewable fatty acid ester production in Clostridium.Nature communication,12, 4368.

     

    发明专利

    1.     一种亮氨酸脱氢酶突变体的构建及其应用,发明专利,专利号:CN108559735B

    2.     一种高效合成α-氨基丁酸的单细胞工厂及其构建与应用,发明专利,专利号:CN106399216B

    3.     一种苏氨酸脱氨酶活性包涵体的制备及其应用,发明专利,专利号:CN105296455B

    4.     Single-cell factory for efficiently synthesizing α-aminobutyric acid and construction and application thereofPCT专利,专利号:US10612054B2

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更新时间:2021.12.20
总访问量:10